Function

Gene Title

Public ID

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change

 

 

 

 

Palmitate

Palmitate + pioglitazone

Palmitate + exenatide

Regulation of gene expression, epigenetic

Chromatin modifying protein 5 (CHMP5)

NM_015961

17.5

 

 

 

Aldolase B, fructose-bisphosphate (ALDOB)

BC005314

17.4

 

 

 

PHD finger protein 20 (PHF20)

AL109965

12.7

 

 

 

ISL1 transcription factor, LIM/homeodomain, (ISL1)

NM_002202

12.4

 

 

 

Potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2)

AF209747

12.1

 

 

 

Nuclear receptor subfamily 2, group F, member 2 (NR2F2)

AL037401

11.9

 

 

 

Ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2 )(autotaxin)

L35594

10.5

 

 

 

Forkhead box N2 (FOXN2)

BF590117

9.7

 

 

 

Transcription factor 4 (TCF4)

BF592782

8.6

 

 

 

Regulator of G-protein signalling 4 (RGS4)

AL514445

8.6

 

 

 

Calreticulin (CALR)

AA910371

8.5

 

 

 

Fibrinogen beta chain (FGB)

NM_005141

8.4

 

 

 

Glutathione S-transferase A1 (GSTA1)

NM_000846

7.4

 

 

 

KH domain containing, RNA binding, signal transduction associated 1 (KHDRBS1)

NM_006559

6.1

 

 

 

Leukocyte-derived arginine aminopeptidase (LRAP)

BE889628

5.5

 

 

 

Ribosomal protein S19 (RPS19)

BC000023

5.5

 

 

 

Cysteine-rich, angiogenic inducer, 61 (CYR61)

NM_001554

5.5

 

 

 

GLIS family zinc finger 3 (GLIS3)

AW025602

5.0

 

 

 

High-mobility group box 1(HMGB1)

N92507

4.2

 

 

 

Regenerating islet-derived 3 alpha (REG3A )

NM_002580

4.1

 

 

 

Adducin 1 (alpha) (ADD1)

NM_001119

3.9

 

 

 

Protease, serine, 2 (trypsin 2)( PRSS2)

NM_002770

3.8

 

 

 

MAX-like protein X (MLX)

N40555

3.7

 

 

 

Eukaryotic translation initiation factor 2-alpha kinase 1 (EIF2AK1)

NM_014413

3.6

 

 

 

Sp4 transcription factor (SP4)

BF438799

3.5

 

 

 

Aldolase B, fructose-bisphosphate (ALDOB)

AV652403

3.5

 

 

 

Meningioma expressed antigen 5 (MGEA5)

AK002091

3.4

 

 

 

Major histocompatibility complex, class I, A (HLA-A)

AI923492

3.4

 

 

 

Runt-related transcription factor 1 (RUNX1)

D43968

3.3

 

 

 

CD53 molecule (CD53)

NM_000560

3.3

 

 

 

Corticotropin releasing hormone (CRH)

NM_000756

3.2

 

 

 

Lymphoid-restricted membrane protein (LRMP)

NM_006152

3.2

 

 

 

Platelet/endothelial cell adhesion molecule (PECAM1 )(CD31 antigen)

AW574504

3.2

 

 

 

Cytochrome P450, family 3, subfamily A, polypeptide 5 (CYP3A5)

X90579

3.0

 

 

 

Major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1)

AI583173

3.0

 

 

 

Retinoic acid receptor responder 2 (RARRES2)

BC000069

3.0

 

 

 

Major histocompatibility complex, class II, DR beta 1 (HLA-DRB1)

NM_002125

2.9

 

 

 

Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A)

AA769818

2.9

 

 

 

Major histocompatibility complex, class II, DR beta 4 (HLA-DRB4)

BC005312

2.8

 

 

 

Glutathione peroxidase 1(GPX1)

NM_000581

2.8

 

 

 

Bombesin-like receptor 3 (BRS3)

Z97632

2.8

 

 

 

Aldolase A, fructose-bisphosphate (ALDOA)

AK026577

2.7

 

 

 

Neuropeptide Y (NPY)

NM_000905

2.7

 

 

 

Major histocompatibility complex, class II, DR alpha (HLA-DRA)

M60333

2.7

 

 

 

Fibroblast growth factor receptor 2 (FGFR2)

NM_022975

2.7

 

 

 

ADAM metallopeptidase domain 28 (ADAM28)

NM_021778

2.7

 

 

 

PHD finger protein 13 (PHF13)

AL039384

2.7

 

 

 

Heparin-binding EGF-like growth factor (HBEGF)

NM_001945

2.7

 

 

 

Amylase, alpha 2A (AMY2A)

NM_004038

2.7

 

 

 

Signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)

BC004973

2.6

 

 

 

Pantothenate kinase 2 (PANK2)

AV703394

2.6

 

 

 

Pancreatic polypeptide (PPY)

M15788

2.5

 

 

 

Phosphofructokinase, muscle (PFKM)

U24183

2.5

 

 

 

Major histocompatibility complex, class II, DR beta 5 (HLA-DRB5)

NM_021983

2.5

 

 

 

PHD finger protein 15 (PHF15)

AI735639

2.5

 

 

 

Guanine nucleotide binding protein (G protein), beta 5 (GNB5)

NM_016194

2.5

 

 

 

Chemokine (C-C motif) receptor 1 (CCR1)

NM_001295

2.4

 

 

 

Colipase, pancreatic (CLPS)

NM_001832

2.4

 

 

 

Nuclear receptor subfamily 4, group A, member 1 (NR4A1)

D85245

2.3

 

 

 

Acetyl-Coenzyme A carboxylase beta (ACACB)

AI970898

2.3

 

 

 

Fms-related tyrosine kinase 1 (FLT1)

AA058828

2.3

 

 

 

Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12)

AI807672

2.3

 

 

 

Vav 3 oncogene (VAV3)

AF118887

2.2

 

 

 

Cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4)

AF182273

2.2

 

 

 

Islet cell autoantigen 1 (ICA1)

L21181

2.2

 

 

 

Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)

NM_012452

2.1

 

 

 

S100 calcium binding protein A8 (S100A8)

NM_002964

2.1

 

 

 

keratin 20 (KRT20)

AI732381

2.1

 

 

 

Mitogen-activated protein kinase kinase 3 (MAP2K3)

AA780381

2.1

2.4

2.0

 

V-set domain containing T cell activation inhibitor 1 (VTCN1)

NM_024626

2.0

 

 

 

Apolipoprotein C-I (APOC1)

W79394

2.0

 

 

 

CDK5 regulatory subunit associated protein 1 (CDK5RAP1)

NM_016408

2.0

 

 

 

Paired box gene 6 (PAX6)

NM_000280

1.9

 

 

 

Phospholamban (PLN)

NM_002667

1.9

 

 

 

DNA-damage-inducible transcript 3 (DDIT3)

BC003637

1.9

 

 

 

Major histocompatibility complex, class II, DM alpha (HLA-DMA)

X76775

1.8

 

 

 

Interleukin 7 receptor (IL7R)

NM_002185

1.8

 

 

 

Solute carrier family 3, member 2 (SLC3A2)

NM_002394

1.8

 

 

 

Epidermal growth factor receptor (EGFR)

BE878463

1.8

 

 

 

Bone morphogenetic protein 2 (BMP2)

NM_001200

1.8

 

 

 

Transforming growth factor, beta 2 (TGFB2)

BF061658

1.7

 

 

 

Kruppel-like factor 5 (KLF5)

AB030824

1.7

 

 

 

Glutamate-ammonia ligase (GLUL)(glutamine synthetase)

U08626

1.7

 

 

 

Melanocortin 4 receptor (MC4R)

NM_005912

1.7

 

 

 

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (NFATC3)

U85430

1.7

 

 

 

YY1 transcription factor (YY1)

AA748649

1.7

 

 

 

EPH receptor B2 (EPHB2)

AL530874

1.7

 

 

 

Mitogen-activated protein kinase kinase kinase 3 (MAP3K3)

BG231756

1.6

2.1

 

 

Activating transcription factor 6 (ATF6)

NM_007348

1.6

 

 

 

Xanthine dehydrogenase (XDH)

U06117

1.6

 

 

 

Acetyl-Coenzyme A carboxylase beta (ACACB)

AI057637

1.6

 

 

 

Forkhead box A3 (FOXA3)

R99562

1.5

2.6

2.6

 

Potassium voltage-gated channel, Isk-related family, member 3 (KCNE3)

AI692703

1.5

 

 

 

Potassium voltage-gated channel, Shab-related subfamily, member 2 (KCNB2)

AF338730

1.5

 

 

 

Thyroid hormone receptor associated protein 1 (THRAP1)

BC024236

 

14.5

15.1

 

LATS, large tumor suppressor, homolog 1 (LATS1)

BC015665

 

11.6

 

 

Phosphoinositide-3-kinase, class 3 (PIK3C3)

BC010388

 

11.4

11.0

 

ATG10 autophagy related 10 homolog (ATG10)

AF318326

 

11.1

12.6

 

Protein tyrosine phosphatase, non-receptor type 18 (PTPN18)

BC031076

 

9.9

11.2

 

Cardiac-MyBP-C associated Ca/CaM kinase (MLCK)

BC039103

 

8.5

9.4

 

Acetyl-Coenzyme A carboxylase alpha (ACACA)

BC007115

 

6.5

6.4

 

Deoxynucleotidyltransferase, terminal (DNTT)

AA585152

 

6.4

6.1

 

GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)(GLI3)

BC032660

 

6.2

6.4

 

Insulin-like growth factor binding protein 2 (IGFBP2)

NM_000597

 

5.7

6.1

 

Rho-guanine nucleotide exchange factor (RGNEF)

AB082529

 

5.1

4.7

 

RAD51 homolog (RAD51)

AL833420

 

4.0

3.8

 

Pre-B-cell leukemia transcription factor 1 (PBX1)

AL832146

 

4.0

4.6

 

Leukemia inhibitory factor receptor (LIFR)

BC038371

 

3.8

4.1

 

Glutamate receptor, metabotropic 3 (GRM3)

AI733361

 

3.4

3.6

 

Pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)( PSCD1)

CA442689

 

3.3

 

 

Cystatin C (CST3)

NM_000099

 

3.1

5.3

 

CAMP responsive element binding protein 1 (CREB1)

AW945589

 

3.0

3.0

 

Transforming growth factor, beta receptor II (TGFBR2)

AI809493

 

2.9

2.9

 

Apoptosis antagonizing transcription factor (AATF)

AW471180

 

2.7

2.6

 

Sterol regulatory element binding transcription factor 1 (SREBF1)

S66168

 

2.5

3.0

 

Glutathione peroxidase 3 (GPX3)

AW149846

 

2.4

4.7

 

Paired box gene 5 (B-cell lineage specific activator)( PAX5)

AW405428

 

2.3

2.2

 

LIM homeobox 4 (LHX4)

AB055704

 

2.2

2.3

 

Arginase (ARG1)

AV649309

 

2.1

2.0

 

Aryl hydrocarbon receptor nuclear translocator (ARNT)

AL137290

 

2.1

2.4

 

Fibroblast growth factor 12 (FGF12)

D60438

 

2.1

2.3

 

RAR-related orphan receptor B (RORB)

R18374

 

2.1

2.1

 

POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)( POU1F1)

NM_000306

 

1.9

1.9

 

Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1 (SERPINH1)

NM_004353

 

1.9

2.9

 

Nodal homolog (NODAL)

AI670948

 

1.8

1.6

 

Fibroblast growth factor 14 (FGF14)

BE221273

 

1.8

 

 

Forkhead box K2 (FOXK2)

AV763408

 

1.8

1.7

 

Pantothenate kinase 2 (PANK2)

AI870137

 

1.8

1.7

 

Fibroblast growth factor 10 (FGF10)

NM_004465

 

1.8

1.6

 

Major histocompatibility complex, class I, B (HLA-B)

L07950

 

1.8

3.3

 

Hepatocyte nuclear factor 4, gamma (HNF4G)

NM_004133

 

1.7

1.7

 

Guanidinoacetate N-methyltransferase (GAMT)

NM_138924

 

1.7

2.0

 

X (inactive)-specific transcript (XIST)

BE644917

 

2.0

 

 

Nuclear receptor subfamily 1, group H, member 2 (NR1H2)

NM_007121

 

1.6

1.6

 

Pantothenate kinase 4 (PANK4)

NM_018216

 

1.6

2.1

 

RAR-related orphan receptor C (RORC)

AI218580

 

1.6

 

 

Retinoid X receptor, beta (RXRB)

BF337038

 

1.5

1.6

 

5'-3' exoribonuclease 1 (XRN1)

BC039314

 

 

12.4

 

Homeodomain interacting protein kinase 1 (HIPK1)

BC036361

 

 

10.1

 

LATS, large tumor suppressor, homolog 1 (LATS1)

BC015665

 

 

10.0

 

CDC14 cell division cycle 14 homolog A (CDC14A)

U29111

 

 

9.4

 

High mobility group AT-hook 2 (HMGA2)

U29113

 

 

8.1

 

Mediator complex subunit 16 (MED16)

AA314406

 

 

7.1

 

Thyroid hormone receptor associated protein 1 (THRAP1)

BC024236

 

 

4.0

 

Insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1)

H93038

 

 

2.6

 

HLA-G histocompatibility antigen, class I, G (HLA-G)

M90684

 

 

2.4

 

NAD(P)H dehydrogenase, quinone 1 (NQO1)

BC000906

 

 

2.3

 

Tubby like protein 4 (TULP4)

AL157491

 

 

2.3

 

Major histocompatibility complex, class II, DR beta 1 (HLA-DRB1)

AJ297586

 

 

2.2

 

X (inactive)-specific transcript (XIST)

BF223193

 

2.0

1.9

 

Rho guanine nucleotide exchange factor (GEF)10 (ARHGEF10)

BC036809

 

2.2

1.9

 

Major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1)

M17565

 

 

1.6

 

Acetyl-Coenzyme A carboxylase beta (ACACB)

AI057637

 

 

1.6

 

Interleukin 10 receptor, beta (IL10RB)

BC001903

 

 

1.5

 

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2)

NM_021804

 

 

1.5

Metabolism

Proprotein convertase subtilisin/kexin type 2 (PCSK2)

AL031664

19.4

 

 

 

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (DDX3Y)

NM_004660

14.0

 

 

 

Thioredoxin domain containing 13 (TXNDC13)

BF572868

13.0

 

 

 

Collagen, type I, alpha 2 (COL1A2)

NM_000089

12.0

 

 

 

SEC24 related gene family, member A (SEC24A)

AJ131244

11.3

 

 

 

Aftiphilin (AFTPH)

BF055271

10.4

 

 

 

Fumarylacetoacetate hydrolase domain containing 1 (FAHD1)

AW070436

9.7

 

 

 

Glutamate decarboxylase 2 (GAD2)

NM_000818

8.8

 

 

 

SH3-domain GRB2-like 2 (SH3GL2)

NM_003026

6.0

 

 

 

Glutathione reductase (GSR)

AI888037

4.7

 

 

 

Matrix metallopeptidase 3 (MMP3)

NM_002422

4.4

 

 

 

Solute carrier family 22, member 5 (SLC22A5)

NM_003060

3.9

2.2

2.2

 

Triosephosphate isomerase 1 (TPI1)

BF116254

3.8

 

 

 

Potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8)

NM_004982

3.3

 

 

 

CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (CDS2)

Y16521

3.3

 

 

 

Syntaxin 7 (STX7)

NM_003569

3.3

 

 

 

Sorbitol dehydrogenase (SORD)

L29008

3.1

 

 

 

Ras homolog gene family, member Q (RHOQ)

BF978689

3.0

 

 

 

Voltage-dependent anion channel 3 (VDAC3)

BC002456

2.8

 

 

 

Argininosuccinate synthetase 1(ASS1)

NM_000050

2.7

 

 

 

ATP-binding cassette, sub-family C, member 1 (ABCC1)

NM_004996

2.7

 

 

 

Prosaposin (PSAP)

NM_002778

2.7

 

 

 

Sodium channel, nonvoltage-gated 1 alpha (SCNN1A)

NM_001038

2.7

 

 

 

Potassium channel tetramerisation domain containing 10 (KCTD10)

AW073741

2.5

 

 

 

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

AFFX-HUMGAPDH/M33197_3

2.5

 

 

 

Pancreatic lipase-related protein 1 (PNLIPRP1)

BC005233

2.5

 

 

 

Pyruvate dehydrogenase kinase, isozyme 3 (PDK3)

NM_005391

2.4

 

 

 

Glutaredoxin (GLRX)

AF162769

2.4

 

 

 

Triosephosphate isomerase 1 (TPI1)

NM_000365

2.2

 

 

 

Ceruloplasmin (ferroxidase) (CP)

AI922198

2.2

 

 

 

Chloride intracellular channel 5 (CLIC5)

AL049313

2.1

 

 

 

Cytochrome b-245, alpha polypeptide (CYBA)

NM_000101

2.1

 

 

 

Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)(SRD5A1)

BC006373

2.0

 

 

 

Carnitine palmitoyltransferase 1A (CPT1A)

BC000185

2.0

 

 

 

Sterol O-acyltransferase 2 (SOAT2)

AF059203

1.9

 

 

 

A kinase (PRKA) anchor protein 10 (AKAP10)

AA456929

1.9

 

 

 

Thioredoxin interacting protein (TXNIP)

AI439556

1.9

 

 

 

Acid phosphatase 1, soluble (ACP1)

BE872974

1.8

 

 

 

Glutathione S-transferase M3 (GSTM3)

AL527430

1.8

 

 

 

Glutathione S-transferase theta 1 (GSTT1)

NM_000853

1.8

 

 

 

Lectin, galactoside-binding, soluble, 2 (LGALS2)

NM_006498

1.8

 

 

 

Potassium inwardly-rectifying channel, subfamily J, member 15 (KCNJ15)

D87291

1.8

 

 

 

Amine oxidase, copper containing 3 (AOC3)

NM_003734

1.7

 

 

 

Chromosome 11 open reading frame 24 (C11orf24)

NM_022338

1.6

 

 

 

Phospholipase A2, group IIA (PLA2G2A)

NM_000300

1.5

 

 

 

Vacuolar protein sorting 13B (COH1)

BC016375

 

15.5

13.3

 

Carboxyl ester lipase (CEL)

BC042510

 

12.8

10.9

 

Potassium channel, subfamily K, member 1 (KCNK1)

AL833343

 

6.7

6.4

 

Choline dehydrogenase (CHDH)

AA609488

 

6.0

6.2

 

Tyrosinase (TYR)

BC027179

 

4.0

4.2

 

Hydroxysteroid (17-beta) dehydrogenase 12 (HSD17B12)

BC012536

 

3.5

3.7

 

NADPH oxidase 1 (NOX1)

AI826277

 

3.2

2.7

 

Lipocalin 2 (LCN2)

NM_005564

 

3.1

3.1

 

Sucrase-isomaltase (alpha-glucosidase)( SI)

NM_001041

 

2.1

2.1

 

Sorbin and SH3 domain containing 1 (SORBS1)

AI377221

 

2.1

1.8

 

Proprotein convertase subtilisin/kexin type 2 (PCSK2)

AU158871

 

2.0

1.7

 

Transferrin receptor (TFRC)

N76327

 

2.0

 

 

Solute carrier family 18, member 2 (SLC18A2)

NM_003054

 

1.9

2.1

 

Paraoxonase 1 (PON1)

U53784

 

1.9

 

 

Mevalonate kinase (MVK)

AU150926

 

1.8

2.1

 

Cystathionine-beta-synthase (CBS)

BE613178

 

1.8

1.9

 

HLA-B associated transcript 3 (BAT3)

BC003133

 

1.6

1.5

 

Alcohol dehydrogenase IB (class I), beta polypeptide (ADH1B)

M21692

 

1.5

 

 

Solute carrier family 6, member 15

BC039443

 

 

12.7

 

DEAD box polypeptide 3, Y-linked (DDX3Y)

BC011022

 

 

12.1

 

Protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform (PPP2R2B)

AF086066

 

 

5.0

 

Recombination activating gene 1 (RAG1)

BC037344

 

 

4.8

 

Lipid storage droplet protein 5 (LSDP5)

BC033570

 

4.6

4.6

 

Transferrin receptor (TFRC)

N76327

 

 

2.0

 

Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (HEXDC)

BM980844

 

2.4

2.4

 

Paraoxonase 1 (PON1)

U53784

 

 

1.8

 

Solute carrier family 14, member 2 (SLC14A2)

AL049328

 

 

1.7

 

Farnesyl diphosphate synthase (FDPS)

AL022163

 

 

1.6

 

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

BF689355

 

 

1.5

Apoptosis

Defender against cell death 1 (DAD1)

NM_001344

9.0

 

 

 

Ras homolog gene family, member B (RHOB)

AI263909

9.4

 

 

 

Engulfment and cell motility 1 (ELMO1)

NM_014800

5.9

 

 

 

Pleckstrin homology-like domain, family A, member 1 (PHLDA1)

AI795908

5.2

 

 

 

Lectin, galactoside-binding, soluble, 1 (galectin 1)( LGALS1)

NM_002305

5.2

 

 

 

Serine/threonine kinase 4 (STK4)

BE222274

4.3

 

 

 

HIV-1 Tat interactive protein 2 (HTATIP2)

NM_006410

3.8

 

 

 

Caspase 10, apoptosis-related cysteine peptidase (CASP10)

NM_001230

2.9

 

 

 

NADH dehydrogenase 1 alpha subcomplex, 13 (NDUFA13)

NM_015965

2.8

 

 

 

Caspase recruitment domain family, member 10 (CARD10)

AY028896

2.5

 

 

 

Secreted phosphoprotein 1 (SPP1)

AB019562

2.4

 

 

 

Inhibitor of growth family, member 4 (ING4)

AA887083

2.3

 

 

 

Brain and reproductive organ-expressed (BRE)

AL566299

2.2

 

 

 

Cytoplasmic FMR1 interacting protein 2 (CYFIP2)

NM_030778

2.1

 

 

 

Nucleolar protein 3 (apoptosis repressor with CARD domain)

AI912351

2.0

 

 

 

Death-associated protein (DAP)

NM_004394

2.0

 

 

 

DNA fragmentation factor, beta polypeptide (DFFB)

NM_004402

2.0

 

 

 

Tumor necrosis factor superfamily, member 13 (TNFSF13)

AF114013

1.9

 

 

 

Mitogen-activated protein kinase kinase kinase 10 (MAP3K10)

NM_002446

1.8

 

 

 

TNF receptor-associated factor 2 (TRAF2)

NM_021138

1.7

 

 

 

Testis-specific kinase 2 (TESK2)

NM_007170

1.6

 

 

 

CD14 molecule (CD14)

NM_000591

1.6

 

 

 

Clusterin (CLU)

M25915

1.6

 

 

 

Growth arrest and DNA-damage-inducible, beta (GADD45B)

AF087853

1.6

 

 

 

Tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A)

NM_016639

1.6

1.9

2.0

 

TNF receptor-associated factor 5 (TRAF5)

BC032830

 

9.4

9.1

 

Mitogen-activated protein kinase 1 (MAPK1)

AL833111

 

6.1

6.3

 

Dedicator of cytokinesis 1 (DOCK1)

AI377320

 

4.0

3.6

 

Serine/threonine kinase 17b ( STK17B)

AI221707

 

3.7

3.9

 

Programmed cell death 6 (PDCD6)

BC02055

 

3.6

3.0

 

Adrenergic, alpha-1A-, receptor (ADRA1A)

BF221864

 

3.6

3.6

 

BCL2/adenovirus E1B interacting protein like (BNIPL)

NM_138279

 

3.0

2.7

 

Sphingosine kinase 1 (SPHK1)

NM_021972

 

2.3

2.4

 

Protein phosphatase 1, regulatory (inhibitor) subunit 13B (PPP1R13B)

AK023188

 

1.7

1.5

 

Tumor necrosis factor receptor superfamily, member 10a (TNFRSF10A)

W65310

 

1.6

 

 

Sterile alpha motif and leucine zipper containing kinase AZK (ZAK)

AI475164

 

1.5

2.0

 

Clusterin (CLU)

M25915

 

 

4.1

 

Apoptosis-inducing factor, mitochondrion-associated, 1(AIFM1)

NM_004208

 

 

1.7

 

NLR family, pyrin domain containing 1 (NLRP1)

NM_021730

 

 

1.7

 

Von Hippel-Lindau tumor suppressor (VHL)

BF972755

 

 

1.6

Response to stimulus

DnaJ (Hsp40) homolog, subfamily A, member 1 (DNAJA1)

NM_001539

12.6

 

 

 

Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3)

AI075407

7.5

 

 

 

Fusion (FUS)( CHOP)

NM_004960

3.6

 

 

 

Major histocompatibility complex, class I, E (HLA-E)

NM_005516

2.8

 

 

 

DnaJ (Hsp40) homolog, subfamily B, member 2 (DNAJB2)

NM_006736

2.6

 

 

 

CD55 molecule, decay accelerating factor for complement (CD55)

BC001288

2.5

 

 

 

CD58 molecule (CD58)

D28586

1.9

 

 

 

Interleukin 1 receptor antagonist (IL1RN)

U65590

1.9

 

 

 

Major histocompatibility complex, class I-related (MR1)

NM_001531

1.7

 

 

 

Paraoxonase 3 (PON3)

L48516

1.5

 

 

 

Activated leukocyte cell adhesion molecule (ALCAM)

BC041127

 

8.9

8.5

 

Decay accelerating factor for complement (DAF )(CD55)

CA448665

 

3.5

8.8

 

T cell receptor alpha locus (TRA@)

AE000659

 

1.8

1.9

 

Lymphotoxin beta (TNF superfamily, member 3)( LTB)

BC018898

 

1.7

1.8

 

Olfactory receptor, family 2, subfamily H, member 1 (OR2H1)

AJ459850

 

 

8.2

 

Recombination activating gene 1 (RAG1)

BC037344

 

 

4.8

 

Tyrosinase (TYR)

BC027179

 

 

4.2

 

Lysozyme (LYZ)

U25677

 

 

3.0

 

REV1 homolog (REV1)

W87784

 

 

2.7

 

Paraoxonase 1 (PON1)

U53784

 

 

1.8

Signal transduction

Chemokine (C-X-C motif) ligand 2 (CXCL2)

M57731

10.7

 

 

 

TRAF family member-associated NFKB activator (TANK)

NM_004180

4.9

 

 

 

CD59 molecule (CD59)

BF983379

2.9

 

 

 

TBC1 domain family, member 4 (TBC1D4)

NM_014832

2.7

 

 

 

Urocortin (UCN)

NM_003353

1.7

 

 

 

c-mer proto-oncogene tyrosine kinase (MERTK)

NM_006343

1.7

 

 

 

Growth differentiation factor 15 (GDF15)

BC000529

 

4.3

1.9

 

SH3 multiple domains 2 (SH3MD2)

AB062480

 

3.0

4.3

 

Relaxin/insulin-like family peptide receptor 1(RXFP1)

NM_021634

 

3.7

3.3

 

SH3-domain GRB2-like 3 (SH3GL3)

U79301

 

1.9

1.9

 

Gastrin-releasing peptide (GRP)

BF110750

 

1.8

1.7

 

Hypothetical LOC554175

BC006530

 

 

8.3

 

Ras and Rab interactor 3 (RIN3)

BC034153

 

 

4.8

 

GTPase, IMAP family member 1 (GIMAP1)

NM_130759

 

 

3.4

 

Mitogen-activated protein kinase associated protein 1 (MAPKAP1)

NM_024117

 

 

1.8

Table 2: Transcripts up-regulated by palmitate, with or without pioglitazone or exenatide, in diabetic human islets.