Demographic and Clinical characteristics

Patients (n = 60)

Control subjects
(n = 40)

P1-value

P2-value

P3-value

Patients with migraine

Patients with TTH

Male/female; # (%)

22/38

1/3

12/28

-

-

-

Age; years

32.0-55.0 (47.83 ± 7.31)

32.0-55.0 (48.55 ± 7.60)

35.55-55.00 (48.35 ± 7.60)

0.494

0.345

0.255

Patients with episodic migraine; # (%)
MoA
MA
Patients with chronic migraine; # (%)
Patients with TTH; # (%)
Duration of migraine; years
Duration of episodic migraine; years
Duration of chronic migraine; years
Duration of TTH; years

35 (62.5%)
25 (44.64%)
10 (17.86%)
21 (37.5%)
4 (6.67%)
1.00-22.00 (8.528 ± 4.27)
2.0-18.0 (6.56 ± 1.45)
1.00-22.00 (9.328 ± 4.27)
-

-
-
-
-
-
-
-
-
5.0-20.0 (15.34 ± 6.33)

9 (22.5 %)
5(12.5%)
3 (7.5%)
1 (2.5%)
11 (27.5%)
5.00-9.00 (3.325 ± 1.05)
-
-
3.0-15.0 (12.23 ± 4.55)

-
-
-
-
-
-
-
-
-

-
-
-
-
-
-
-
-
0.255

-
-
-
-
-
-
-
-
0.012

Frequency of headache attacks; #/month (%)
Low-frequency (<4/month)
High-frequency (≥4/month)

5 (8.33%)
51 (85%)

1 (1.67%)
3 (5%)

4 (10%)
2 (5%)

-
-

-
-

-
-

BMI; kg/m2

29.07-55.55 (39.01 ± 6.05)

29.07-55.55(28.55 ± 6.56)

26.20-53.50 (30.52 ± 4.59)

0.253

0.865

0.365

Degree of obesity; # (%)
normal: 18.5-24.9 kg/m2
Overweight: 25.0-29.9 kg/m2
Obese: 30.0-34.9 kg/m2
Morbidly obese: >35.0 kg/m2

0
2 (3.33%)
21 (35%)
33 (55%)

0
3 (5%)
1 (1.67%)
0

14 (35%)
16 (40%)
2 (5%)
0

-
-
-
-

-
-
-
-

-
-
-
-

WC; cm

93.0-136.0 (126.27 ± 9.84)

93.0-136.0 (108.36 ± 9.99)

100.0-132.0 (87.05 ± 5.32)

0.050

0.053

0.058

SBP; mmHg
DBP; mmHg

110.0-180.0 (150.92 ± 16.86)
70.0-110.0 (105.75 ± 6.56)

100.0-150.0 (135.060 ± 16.33)
70.0-100.0 (80.20 ± 8.10)

100.0-130.0 (120.0 ± 0.0)
60.0-85.0 (80.0 ± 0.0)

0.052
0.054

0.432
0.405

0.052
0.050

Duration of T2DM; years
Duration of obesity; years
Duration of HTN; years

2.0-20.0 (5.98 ± 3.60)
2.0-20.0 (8.75 ± 4.47)
1.0-18.0 (5.12 ± 3.44)

2.0-20.0 (6.24 ± 2.50)
2.0-20.0 (5.04 ± 2.08)
1.0-18.0 (4.92 ± 2.16)

-
-
-

-
-
-

-
0.057
-

-
-
-

Degree of control on anti-diabetics treatment
Controlled; # (%)
Uncontrolled; # (%)
Degree of control on anti-hypertensive treatment
Controlled; # (%)
Uncontrolled; # (%)
Degree of control on lipid lowering treatment
Controlled; # (%)
Uncontrolled; # (%)

23 (38.33%)
33 (55%)

24 (40%)
32 (53.33%)

23 (38.33%)
33 (55%)

3 (5%)
1 (1.67%)

2 (3.33%)
2 (3.33%)

4 (6.67%)
0

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

Data are expressed as range, meanąSD; number (%); MoA, migraine without aura; MA, migraine with aura; TTH, tension type headache; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; T2DM, type 2 diabetes mellitus; HTN, hypertension
Significance: P1: migraine versus controls; P2: TTH versus controls; P3: migraine versus TTH
Table 1: Demographic, anthropometric and clinical characteristics of the studied groups.