Parameters Healthy group
(n=11)
(mean ± SE)
Diseased group
(n=44)
(mean ± SE)
P value
Clinical      
Age, days 12,5 ± 1,59 12,3 ± 1,89 0.9700
Temperature °C 38.5 ± 0.13 37.0 ± 0.22 0.000
Pulsation, beats/min 114 ± 2.87 97.7 ± 7.65 0.057
Respiration, breaths/min 27.7 ± 1.09 32.5 ± 2.86 0,101
Dehydration, (%) 3.64 ± 0.20 9.53 ± 0.17 0.000
Capillar refill time, sec 2.09 ± 0.09 3.71 ± 0.11 0.000
Suckling reflex - Weak to absent  
Posture - Recumbent  
Scleral injection - ­  
Focal infection   No  
Feces - Watery, mucoid, bloody  
Blood Gas Analysis and CBC      
Blood pH 7.37 ± 0.01 7.20 ± 0.05 0.003
pCO2, mmHg 49.2 ± 1.05 47.4 ± 3.30 0.609
pO2, mmHg 22.4 ± 1.15 21.5 ± 1.70 0.676
HCO3, mEq/L 28.6 ± 0.78 20.9 ± 2.92 0.020
Base excess, mEqlL 3.46 ± 0.58 -5.82 ± 3.43 0.016
O2 saturation 36.5 ± 3.15 26.5 ± 3.85 0.054
White blood cells, ×103/μL 10.4 ± 0.92 20.4 ± 2.82 0.003
Red blood cells, ×106/μL 7.72 ± 0.34 7.93 ± 0.45 0.716
Thrombocytes,×105/μL 454 ± 50.3 726 ± 148 0.098
Mean corpuscular volume, fL 32.9 ± 0.91 35.9 ± 1.02 0.037
Mean corpuscular Hb, pg 11.9 ± 0.63 11.6 ± 0.27 0.658
Mean cell Hb concentration, g/dL 36.7 ± 2.29 32.6 ± 0.49 0.110
Hematocrit, % 25.5 ± 1.57 28.8 ± 2.17 0.227
Hemoglobin, g/dL 9.12 ± 0.30 9.34 ± 0.63 0.753
Biochemical      
Total Protein, g/dL 5,18 ± 0.15 5.32 ± 0.23 0.632
Fibrinogen, mg/dL 837 ± 63.2 293.± 23.4 0.000
ImmunoglobulinG, mg/dL 1334 ± 4.20 343 ± 12.5 0.000
Creatinine, mg/dL 1.04 ± 0.05 2.35 ± 0.75 0.096
Glucose, mg/dL 72.4 ± 4.40 64.0 ± 7.90 0.359
Lactate, mEqlL 1.56 ± 0.25 2.40 ± 0.54 0.175
AST, (U/L) 41.0 ± 3.00 132 ± 24.2 0.001
GGT, (U/L) 47.5 ± 7.52 105.6 ± 24.2 0.032
CPK, (U/L) 73.0 ± 13.4 353 ± 64.5 0.000
Na, mEqlL 142 ± 1.24 138 ± 2.55 0.192
K, mEq/L 4.21 ± 0.10 4.79 ± 0.33 0.113
Ionized Ca, mEq/L 0.96 ± 0.04 1.01 ± 0.05 0.420
Table 1: Clinical and laboratory data of healthy and ill calves