Healthy group
(n=11)
Diseased group
(n=44)
P value
Water Soluble Metabolites      
Formate 0.010 ± 0.002 0.008 ± 0.002 0.021
Niacinamide 0.0002 ± 0.0003 0.003 ± 0.002 0.0005
Lactate 1.47 ± 0.54 3.18 ± 3.3 0.08
a-Glucose 0.12 ± 0.033 0.13 ± 0.132 0.83
Mannose 0.0046 ± 0.0009 0.003 ± 0.0042 0.173
Creatine 0.057 ± 0.018 0.11 ± 0.06 0.0022
Lactose 0.01 ± 0.004 0.06 ± 0.06 5.2e-5
Choline+Phosphocholine 0.026 ± 0.004 0.041 ± 0.03 0.003
Acetate 0.062 ± 0.02 0.031 ± 0.012 0.0003
Lysine+Arginine 0.026 ± 0.01 0.008 ± 0.012 0.0035
Isopropanol 0.004 ± 0.003 0.031 ± 0.024 0.0001
3-hyroxyubutyrate 0.028± 0.006 0.065 ± 0.03 0.001
2-Methylglutarate 0.0083 ± 0.0027 0.016 ± 0.005 1.76e-5
Lipid Metabolites      
Sphingomyeline 0.016 ± 0.003 0.002 ± 0.0006 5.59e-6
UFA 0.594 ± 0.156 0.15 ± 0.09 4.36e-5
Glycerol-P-Lipids 0.053 ± 0.013 0.023 ± 0.013 0.0004
TAG 0.043 ± 0.014 0.023 ± 0.012 0.015
Cholesterol 0.33 ± 0.04 0.089 ± 0.044 5.59e-6
Phospholipids 2.41 ± 0.18 2.046 ± 0.21 0.0004
PUFA 0.252 ± 0.065 0.073 ± 0.056 7.4e-5
FA 2.259 ± 0.408 0.508 ± 0.364 9.98e-6
Total Lipids (CH2)n 12.9 ± 2.29 2.87 ± 1.38 5.59e-6
Total Lipids (CH3)n 5.49 ± 0.73 0.95 ± 0.62 5.59e-6
Table 2: The numbers are relative intensity to TMSP instead of absolute concentration [μmol/ml].