Metabolite Diabetes detected by   fPC1 Metabolite Diabetes detected by fPC2 2-Hydroxyisobutyrate 2-Hydroxyisobutyrate 3-Hydroxyisovalerate - Acetate Acetate Acetone - Betaine Betaine Creatine - Creatinine - Dimethylamine Dimethylamine Glucose Glucose Glycine Glycine Glycolate Glycolate Hypoxanthine - Isopropanol - Lactate - Maleate Maleate Mannitol Mannitol Methanol Methanol Methylamine Methylamine N,N-Dimethylglycine N,N-Dimethylglycine Succinate - Tartrate Tartrate Taurine Taurine β-Alanine - π -Methylhistidine -

Table 4: Compounds detected in actual samples. Left column summarizes the ones detected by fPC1 and right column summarizes the ones detected by fPC2. Compound detected with fPC1 are potential biomarkers in human urine for diabetes. Compound detected with fPC2 indicating most variations in the normal and diabetic samples. Compounds in red have been reported abnormal in human urine in HMDB.