Body mass index No. at risk No. of incident cases Crude Adjusted
      OR 95% CI p value OR 95% CI p value
All participants (n=456)             Model 1  
Quartile 1 114 7 ref - - ref - -
Quartile 2 114 15 2.32 0.91-5.92 0.08 3.46 1.17-10.21 0.02
Quartile 3 112 9 0.88 0.38-2.01 0.76 0.72 0.29-1.78 0.48
Quartile 4 116 14 1.44 0.73-2.84 0.29 1.48 0.67-3.27 0.34
P value for trend     0.25     0.09    
BMI <24 (n=359)             Model 2  
Quartile 1 87 2 ref - - ref - -
Quartile 2 92 8 4.05 0.84-19.62 0.08 4.81 0.85-27.12 0.08
Quartile 3 89 7 1.53 0.49-4.77 0.47 0.69 0.18-2.62 0.59
Quartile 4 91 2 0.41 0.90-1.89 0.25 0.15 0.03-0.89 0.04
P value for trend     0.15     0.03    
BMI ≥ 24 (n=97)                
Quartile 1 27 5 ref - -      
Quartile 2 22 7 2.05 0.55-7.7 0.29      
Quartile 3 23 3 0.46 0.12-1.83 0.27      
Quartile 4 25 12 3.67 1.37-9.84 0.01      
P value for trend     0.04          
Model 1: Adjusted for age, WHR, HDL cholesterol, LDL cholesterol, and BMI.
Model 2: Adjusted for age, WHR, total cholesterol, and LDL cholesterol.
Abbreviations: BMI: Body Mass Index; CI: Confidence Intervals; HDL: High-Density Lipoprotein; LDL: Low-Density Lipoprotein; OR: Odds Ratios; WHR: Waist to Hip Ratio
Table 1: Baseline characteristics of study participants by quartile of serum estradiol.