Figure 5: Metabolic profiling of LoVo cells treated with 10μM ADMA for 96h in serum starvation medium. (A-C) The PCA score plots for all three groups, C vs. SS, and SS vs. ADMA, respectively. (D) Summary of main differential metabolites altered by serum starvation and ADMA in glucose metabolism and TCA cycle. C: Control Group; SS: Serum Starvation Group; ADMA: 10 μM ADMA for 96 h in serum starvation medium. The dashed and black arrows in metabolic processes represent indirect or direct reactions.