| Metabolites |
RT_min |
Mean ± SD
|
Fold Change |
P value |
| |
|
C |
SS |
ADMA |
SS/C |
ADMA/C |
SS vs. C |
ADMA vs SS |
| HypotaurineLC |
3.07 |
2.060 ±0.340 |
1.174 ±0.157 |
1.205 ±0.240 |
0.570 |
0.585 |
0.001 |
0.815 |
| 2,3-Diaminopropionic acid LC |
3.40 |
0.921 ±0.055 |
0.684 ±0.073 |
0.740 ±0.083 |
0.742 |
0.803 |
0.000 |
0.290 |
| Aminoadipic acid LC |
3.54 |
2.209 ±0.275 |
1.159 ±0.161 |
1.084 ±0.133 |
0.525 |
0.491 |
0.000 |
0.443 |
| 5-Aminolevulinic acid LC |
3.63 |
0.409 ±0.125 |
0.174 ±0.020 |
0.169 ±0.015 |
0.425 |
0.412 |
0.003 |
0.648 |
| Asparagine LC |
3.67 |
0.990 ±0.196 |
0.476 ±0.060 |
0.447 ±0.079 |
0.481 |
0.451 |
0.001 |
0.524 |
| N-Acetyl-D-glucosamine LC |
3.75 |
0.092 ±0.006 |
0.141 ±0.013 |
0.148 ±0.011 |
1.532 |
1.613 |
0.000 |
0.360 |
| Glutathione LC |
3.97 |
17.440 ±2.498 |
0.281 ±0.039 |
0.229 ±0.131 |
0.016 |
0.013 |
0.000 |
0.416 |
| Deoxyguanosine LC |
4.03 |
0.756 ±0.077 |
1.079 ±0.253 |
0.985 ±0.200 |
1.427 |
1.302 |
0.026 |
0.531 |
| Pyruvic acid GC |
5.37 |
0.175 ±0.054 |
0.091 ±0.026 |
0.152 ±0.041 |
0.520 |
0.868 |
0.014 |
0.022 |
| 3-Hydroxybutyric acid GC |
6.93 |
0.024 ±0.007 |
0.044 ±0.010 |
0.040 ±0.010 |
1.827 |
1.661 |
0.007 |
0.548 |
| Urea GC |
8.00 |
0.009 ±0.001 |
0.017 ±0.002 |
0.017 ±0.001 |
1.835 |
1.924 |
0.000 |
0.406 |
| Ethanolamine GC |
8.48 |
0.043 ±0.010 |
0.171 ±0.018 |
0.189 ±0.025 |
4.002 |
4.418 |
0.000 |
0.235 |
| Proline GC |
8.92 |
1.285 ±0.439 |
2.946 ±0.368 |
2.691 ±0.545 |
2.292 |
2.094 |
0.000 |
0.413 |
| Glycine GC |
9.05 |
1.426 ±0.389 |
3.025 ±0.581 |
2.765 ±0.385 |
2.121 |
1.939 |
0.001 |
0.429 |
| Succinic acid GC |
9.06 |
0.041 ±0.010 |
0.027 ±0.003 |
0.026 ±0.003 |
0.655 |
0.630 |
0.014 |
0.595 |
| Glyceric acid GC |
9.39 |
0.026 ±0.010 |
0.062 ±0.005 |
0.072 ±0.004 |
2.426 |
2.820 |
0.000 |
0.006 |
| Uracil GC |
9.46 |
0.060 ±0.006 |
0.111 ±0.022 |
0.129 ±0.042 |
1.837 |
2.151 |
0.001 |
0.403 |
| Fumaric acid GC |
9.50 |
0.124 ±0.026 |
0.025 ±0.004 |
0.025 ±0.005 |
0.202 |
0.199 |
0.000 |
0.927 |
| Aminomalonic acid GC |
11.22 |
0.011 ±0.007 |
0.025 ±0.008 |
0.023 ±0.009 |
2.291 |
2.095 |
0.015 |
0.692 |
| Nicotinamide GC |
11.23 |
0.053 ±0.064 |
0.164 ±0.034 |
0.184 ±0.045 |
3.084 |
3.459 |
0.009 |
0.451 |
| Malic acid GC |
11.44 |
0.448 ±0.090 |
0.071 ±0.019 |
0.062 ±0.007 |
0.159 |
0.139 |
0.000 |
0.362 |
| Methionine GC |
11.80 |
0.089 ±0.024 |
0.123 ±0.011 |
0.122 ±0.015 |
1.390 |
1.370 |
0.018 |
0.846 |
| Aspartic acid GC |
11.82 |
1.754 ±0.454 |
0.649 ±0.108 |
0.616 ±0.110 |
0.370 |
0.351 |
0.001 |
0.644 |
| 5-oxoproline GC |
11.86 |
4.664 ±2.358 |
1.091 ±0.107 |
0.831 ±0.472 |
0.234 |
0.178 |
0.010 |
0.264 |
| 4-hydroxy-proline GC |
11.91 |
0.052 ±0.020 |
0.004 ±0.001 |
0.004 ±0.001 |
0.075 |
0.069 |
0.001 |
0.620 |
| Threonic acid GC |
12.20 |
0.024 ±0.009 |
0.006 ±0.001 |
0.006 ±0.000 |
0.244 |
0.265 |
0.002 |
0.271 |
| 2-Hydroxyglutaric acid GC |
12.47 |
0.008 ±0.002 |
0.004 ±0.001 |
0.003 ±0.000 |
0.485 |
0.444 |
0.004 |
0.358 |
| Glutamate GC |
12.99 |
1.828 ±0.522 |
0.193 ±0.031 |
0.187 ±0.033 |
0.106 |
0.102 |
0.000 |
0.749 |
| Homocysteine GC |
13.51 |
0.002 ±0.000 |
0.009 ±0.001 |
0.008 ±0.002 |
5.833 |
5.234 |
0.000 |
0.380 |
| Xylose GC |
13.81 |
0.075 ±0.019 |
0.208 ±0.030 |
0.234 ±0.019 |
2.765 |
3.121 |
0.000 |
0.127 |
| Arabinose GC |
14.15 |
0.002 ±0.001 |
0.005 ±0.002 |
0.005 ±0.001 |
1.990 |
2.076 |
0.014 |
0.815 |
| Glycerol 3-phosphate GC |
14.68 |
0.033 ±0.006 |
0.069 ±0.008 |
0.069 ±0.008 |
2.096 |
2.096 |
0.000 |
0.998 |
| Glutamine GC |
14.72 |
0.867 ±0.147 |
0.052 ±0.018 |
0.044 ±0.017 |
0.060 |
0.051 |
0.000 |
0.470 |
| 3-Phosphoglyceric acid GC |
15.17 |
0.006 ±0.002 |
0.034 ±0.012 |
0.026 ±0.007 |
5.861 |
4.459 |
0.001 |
0.223 |
| Myristic acid GC |
15.37 |
0.012 ±0.002 |
0.008 ±0.001 |
0.009 ±0.001 |
0.664 |
0.709 |
0.001 |
0.461 |
| Adenine GC |
15.71 |
0.031 ±0.008 |
0.016 ±0.002 |
0.016 ±0.003 |
0.510 |
0.505 |
0.004 |
0.912 |
| Fructose GC |
15.94 |
0.018 ±0.003 |
0.014 ±0.001 |
0.018 ±0.002 |
0.756 |
0.999 |
0.012 |
0.001 |
| Mannose GC |
16.08 |
0.001 ±0.000 |
0.011 ±0.001 |
0.011 ±0.002 |
7.663 |
7.346 |
0.000 |
0.619 |
| Glucose GC |
16.21 |
0.016 ±0.003 |
0.048 ±0.006 |
0.049 ±0.012 |
3.017 |
3.118 |
0.000 |
0.793 |
| Lysine GC |
16.27 |
0.135 ±0.032 |
0.236 ±0.026 |
0.238 ±0.037 |
1.756 |
1.766 |
0.001 |
0.945 |
| Pentadecanoic acid GC |
16.37 |
0.022 ±0.002 |
0.060 ±0.010 |
0.067 ±0.016 |
2.765 |
3.103 |
0.000 |
0.395 |
| Galactose GC |
16.40 |
0.002 ±0.001 |
0.008 ±0.001 |
0.008 ±0.002 |
3.365 |
3.416 |
0.000 |
0.909 |
| Glucuronic acid GC |
16.63 |
0.004 ±0.001 |
0.013 ±0.001 |
0.013 ±0.002 |
3.570 |
3.619 |
0.000 |
0.883 |
| Pantothenic acid GC |
17.03 |
0.042 ±0.011 |
0.011 ±0.002 |
0.012 ±0.001 |
0.261 |
0.275 |
0.000 |
0.575 |
| Palmitoleic acid GC |
17.20 |
0.048 ±0.008 |
0.108 ±0.024 |
0.125 ±0.036 |
2.244 |
2.608 |
0.001 |
0.392 |
| Ribose GC |
19.10 |
0.082 ±0.024 |
0.033 ±0.014 |
0.025 ±0.016 |
0.401 |
0.301 |
0.004 |
0.404 |
| Oleic acid GC |
19.44 |
0.059 ±0.008 |
0.141 ±0.021 |
0.159 ±0.037 |
2.401 |
2.708 |
0.000 |
0.376 |
| Glucose 1(6)-phosphate GC |
20.99 |
0.003 ±0.001 |
0.020 ±0.003 |
0.012 ±0.001 |
7.816 |
4.661 |
0.000 |
0.001 |
| Eicosenoic acid GC |
21.36 |
0.004 ±0.001 |
0.007 ±0.001 |
0.008 ±0.002 |
1.833 |
2.148 |
0.000 |
0.166 |
| Orotidine GC |
21.45 |
0.007 ±0.002 |
0.026 ±0.011 |
0.031 ±0.007 |
3.986 |
4.733 |
0.004 |
0.420 |
| Myo-Inositol, phosphate GC |
21.71 |
0.013 ±0.002 |
0.026 ±0.002 |
0.031 ±0.004 |
1.903 |
2.335 |
0.000 |
0.030 |
| 5,8,11,14,17-Eicosapentaenoic acid GC |
22.41 |
0.020 ±0.001 |
0.027 ±0.005 |
0.027 ±0.005 |
1.311 |
1.316 |
0.017 |
0.971 |
| Glycerol 1-hexadecanoate GC |
22.49 |
0.060 ±0.004 |
0.001 ±0.000 |
0.001 ±0.000 |
0.023 |
0.021 |
0.000 |
0.441 |
| Inosine GC |
22.52 |
0.043 ±0.013 |
0.197 ±0.016 |
0.191 ±0.018 |
4.642 |
4.487 |
0.000 |
0.553 |
| Adenosine GC |
22.91 |
0.020 ±0.005 |
0.048 ±0.014 |
0.044 ±0.017 |
2.420 |
2.198 |
0.003 |
0.664 |
| Guanosine GC |
23.87 |
0.044 ±0.017 |
0.098 ±0.010 |
0.098 ±0.026 |
2.244 |
2.238 |
0.000 |
0.984 |
| Cholesterol GC |
27.66 |
2.287 ±0.295 |
5.476 ±0.736 |
5.715 ±1.608 |
2.394 |
2.499 |
0.000 |
0.769 |
