| Biomarkers |
Chemical shift δ/ppm |
PLS-DA VIP |
one-way ANOVAa |
| p.value |
FDRb |
| Serotonin (Ser) |
3.308 (t) |
3.998 |
6.62E-17 |
1.79E-15 |
| Melatonin(Mel) |
7.192 (s) |
1.217 |
>0.05 |
- |
| Glycerophosphorylcholine (GPC) |
3.268 (s) |
1.611 |
>0.05 |
- |
| 4-Hydroxyproline (Hyp) |
3.344 (d) |
2.651 |
8.83E-05 |
2.17E-04 |
| L-Glutamine (Gln) |
2.156 (m) |
2.507 |
8.79E-14 |
1.19E-12 |
| N-Acetylglutamate (NAG) |
2.048 (s) |
1.27 |
2.59E-03 |
5.00E-03 |
| Creatine (Cr) |
3.936 (s) |
1.191 |
1.17E-05 |
3.93E-05 |
| O-Acetylcarnitine (OAC) |
2.148 (s) |
2.09 |
1.53E-07 |
8.24E-07 |
| 3-Methyl-2-oxovalerate (MOV) |
0.832 (d) |
1.223 |
2.25E-02 |
2.76E-02 |
| Methylmalonate (MMA) |
1.120 (d) |
1.52 |
1.19E-02 |
1.61E-02 |
| Xanthine (Xa) |
7.876 (s) |
2.387 |
3.26E-03 |
5.86E-03 |
| Isovaleric acid (IVA) |
2.200 (d) |
2.104 |
1.82E-10 |
1.64E-09 |
| Succinate (Suc) |
2.410 (s) |
1.01 |
1.50E-02 |
1.93E-02 |
| Citrate (Cit) |
2.532 (t) |
1.156 |
2.25E-03 |
4.67E-03 |
| α-Ketoglutarate (Kg) |
2.460 (t) |
1.445 |
4.77E-03 |
8.05E-03 |
| Glycine (Gly) |
3.560 (s) |
2.248 |
4.94E-08 |
3.33E-07 |
| Alanine (Ala) |
1.484 (d) |
1.225 |
>0.05 |
- |
| Threonine (Thr) |
3.724 (m) |
2.042 |
1.13E-06 |
5.07E-06 |
| N-methylnicotinamide (NMND) |
8.936 (d) |
1.965 |
7.75E-03 |
1.16E-02 |
| 3-hydroxymandelate (Hym) |
7.280 (d) |
1.238 |
7.86E-05 |
2.17E-04 |
| Taurine (Tau) |
3.344 (t) |
2.651 |
8.83E-05 |
2.17E-04 |
| Hippurate (Hip) |
3.980 (d) |
1.115 |
6.66E-03 |
1.06E-02 |
| Indole-3-acetate (IAA) |
7.492 (d) |
2.633 |
1.56E-03 |
3.51E-03 |
| 4-Hydroxybenzoic acid (HBA) |
7.772 (d) |
1.717 |
>0.05 |
- |
| Imidazole (Imi) |
8.340 (s) |
1.226 |
>0.05 |
- |
|
