Groups |
GPx (nmol of NADPH oxidized/min/mg protein) |
GR (nmol of NADPH oxidized/min/mg protein) |
GST (nmol of NADPH oxidized/min/mg protein) |
CAT (nmol of H2O2consumed/min/mg protein) |
SOD (nmol (−)-epinephrine protected from oxidation/min/mg protein) |
Control |
667.49± 51.12 |
787.30 ± 60.15 |
1816.12 ±199.60 |
241.98±12.52 |
1270.94 ±199.60 |
Te |
453.87* ± 38.62
(-32.01 %) |
419.29* ± 43.73
(-46.74 %) |
1064.44* ±128.71
(-41.39 %) |
177.82* ± 37.94
(-26.51 %) |
644.93* ± 52.02
(-49.26 %) |
Z1+Te |
608.35# ± 65.60
(34.03 %) |
629.64#± 94.81 (50.16 %) |
1300.22#± 118.08
(22.13 %) |
225.07#±
19.14
(26.57 %) |
977.11# ± 93.13
(51.50 %) |
Z2+Te |
634.59#± 49.09
(39.82 %) |
715.90##± 54.78
(70.74 %) |
1587.9#9 ± 83.97
(49.19 %) |
236.39#±
18.21
(32.93 %) |
1072.5##± 160.04
(66.29 %) |
Te toxicity leads to significant depletion on the activity of antioxidant enzymes (GPx, GR, GST, CAT and SOD) in Te groups as compared to control group (*p<0.05 vs.
control group). Administration of zingerone (50 and 100 mg/kg b. wt.) significantly improved the activity of these enzymes in Z1+L and Z2+L groups as compared to Te
group (#p<0.05, ##p<0.05 vs. Te group). Values in parentheses show the percentage increase or decrease with respect to their control. Values are expressed as Mean ±
SEM of 8 animals.