| Publication |
Technique |
Important changes |
Sample type |
Amount (n=) |
| Delbridge et al. |
MRS |
Lipids 1.7 ppm and 0.9 ppm amino acids regions ratio |
Tissue |
98 |
| King et al. |
MRS |
Choline/Creatine ratio and FA |
Tissue |
13 |
| Mackinnon et al. |
2D 1H MRS |
cholesterol/cholesteryl esters and di-/triglycerides |
Tissue |
93 |
| Gupta et al. |
MRS |
Choline |
Tissue |
8 |
| Jordan et al. |
1HRMAS |
Lipids 1.7 ppm and 0.9 ppm amino acids regions ratio |
Tissue |
13 |
| Toregrrossa et al. |
1HRMAS |
Lactate, taurine, choline, phosphocholine, myo-inositol, scylloinositol and unknown compounds |
Tissue |
72 |
| Yoshioka et al. |
1H NMR |
Dolichols, cholesterol, acyl chain double bounds, PC+SPH |
Tissue |
61 |
| Raffelt et al |
31P NMR |
PR+SM and PC |
Plasma |
70 |
| Deja et al. |
1H NMR |
Alanine, methionine, acetone, glutamate, glycine, lactate, tyrosine, phenylalanine, hypoxanthine, scyllo- and myo-inositol |
Tissue |
64 |
| S Guo et al |
FT-ICR-MS |
PC(34:1), PC(36:1), PC(38:6), PA(36:2), PA(36:3), PA(38:3), PA(38:4), PA(38:5), PA(40:5) and SM(34:1) |
Tissue/serum |
36/289 |
| Ishikawa et al. |
IMS, MS/MS |
PC (16:0/18:1 and 16:0/18:2) and SPH (d18:0/16:1 ) |
Tissue |
7 |
| Yao et al |
LC-MS |
FFA and 3-hydroxybutyric acid |
Serum |
140 |
| L Guo et al. |
GC-MS |
Ethyl hexanol, phenol, 4-hydroxybutanoic acid |
Exhaled breath |
96 |
|
| Table 1: Summary of results of metabolomic studies of changes in the thyroid gland [27,28,34-39,41,43,44,47,53]. |
