Metabolite set Enrichent Analysis (MSEA) was implemented to test metabolic pathways enrichment among tuberculous pleural effusion group, transudative pleural effusion group and malignant pleural effusion group. MSEA indicated that protein biosynthesis, pyruvate metabolism, different kinds of amino acid metabolism, glucose-alanine cycle, insulin signaling, ureacycle, glycolysis, citric acid cycle, betaine, starch, sphingolipid, propanoate, phospholipid, galactose, pyrimidine, purine metabolism are significantly associated with these diseases
Figure 3: Pleural effusion enrichment analysis.