|
NC |
NIT-NA |
NIT-MA |
NIT-LA; |
HOMA-IR; |
1.90 ± 0.50 |
3.73 ± 1.19a |
;4.64 ± 3.47a |
6.31 ± 2.62a |
HOMA-β |
97.89 ± 22.90 |
56.21 ± 24.31a |
46.58 ± 38.08a |
38.55 ± 21.7a |
QUICKI |
0.62 ± 0.04 |
0.53 ± 0.08a |
;0.53 ± 0.06a |
0.51 ± 0.17a |
Nampt (ng/mL) |
8.56 ± 3.49 |
19.89 ± 4.01a |
29.07 ± 6.25ab |
37.64 ± 5.91abc |
IL-1β (pg/mL) |
76.96 ± 25.97 |
141.67 ± 35.11a |
195.45 ± 49.26ab |
276 ± 64.57abc |
|
aCompared with NC, P < 0.05; bCompared with NIT-NA, P < 0.05; cCompared with NIT-MA, P < 0.05
NC = Control group; NIT-NA = Normoalbuminuria in Non-Insulin Therapy group; NIT-MA = Microalbuminuria in Non-Insulin Therapy group; NIT-LA = Large Amount of
albuminuria group in non-insulin therapy group; HOMA-IR = Homeostasis Model Assessment; HOMA-β = Homa beta cell function index; QUICKI = Quantitative Insulin
Sensitivity Check Index; Nampt = Nicotinamide phosphoribosyltransferase ; IL-1β = Interleukin-1β |
Table 3: Nampt, IL-1β, islet function and insulin resistance extent in NC and NIT group. |