NC NIT-NA NIT-MA NIT-LA;
HOMA-IR; 1.90 ± 0.50 3.73 ± 1.19a ;4.64 ± 3.47a 6.31 ± 2.62a
HOMA-β 97.89 ± 22.90 56.21 ± 24.31a 46.58 ± 38.08a 38.55 ± 21.7a
QUICKI 0.62 ± 0.04 0.53 ± 0.08a ;0.53 ± 0.06a 0.51 ± 0.17a
Nampt (ng/mL) 8.56 ± 3.49 19.89 ± 4.01a 29.07 ± 6.25ab 37.64 ± 5.91abc
IL-1β (pg/mL) 76.96 ± 25.97 141.67 ± 35.11a 195.45 ± 49.26ab 276 ± 64.57abc
aCompared with NC, P < 0.05; bCompared with NIT-NA, P < 0.05; cCompared with NIT-MA, P < 0.05
NC = Control group; NIT-NA = Normoalbuminuria in Non-Insulin Therapy group; NIT-MA = Microalbuminuria in Non-Insulin Therapy group; NIT-LA = Large Amount of albuminuria group in non-insulin therapy group; HOMA-IR = Homeostasis Model Assessment; HOMA-β = Homa beta cell function index; QUICKI = Quantitative Insulin Sensitivity Check Index; Nampt = Nicotinamide phosphoribosyltransferase ; IL-1β = Interleukin-1β
Table 3: Nampt, IL-1β, islet function and insulin resistance extent in NC and NIT group.