Probe ID miRNA Name Log2 Fold Change Linear Fold Change 2110 hsa-miR-519a-3p 2.487678918 3.678656793 1310 hsa-miR-29c-3p 2.1917789876 2.453657509 1865 hsa-miR-382-3p -2.348987679 -2.346756764 1863 hsa-miR-485-5p -1.678675674 -2.289965768

Table 3: Cisplatin induces the microRNA deregulation in SCC-11M cells. SCC-11 cells and SCC-11M cells were exposed to control medium or 10μg/ml cisplatin for 16hours. MicroRNA shown to be up and downregulated in SCC-11M cells compared to SCC-11 cells upon cisplatin exposure were tabulated according to the fold change. ID represents the location of the probe on the microRNA chip [22]. Data were expressed as means ± SD from three independent experiments. Differences in variables between experimental and control groups were assessed by using the Student t test (p < 0.05).