Analytes

Concentration

(μg·L-1)

Intra-day(n=5)

Inter-day(n=15)

Mean

Accuracy

(% )

Precision

 (%)

Mean

Accuracy

(% )

Precision

 (%)

AZT

40

38.1

95.2

11.0

38.5

96.3

9.4

 

320

310.4

96.9

7.5

313.9

98.1

9.0

 

2560

2568.0

100.3

2.1

2610.7

102.0

6.8

3TC

40

40.2

100.6

8.7

38.1

95.3

8.5

 

320

297.6

93.0

4.6

308.5

96.4

8.5

 

2560

2516.0

98.2

10.4

2566.0

100.2

9.1

d4T

40

37.6

94.0

10.1

38.2

95.4

8.7

 

320

302.0

94.4

4.8

312.3

97.6

9.4

 

2560

2586.0

100.9

2.1

2590.0

101.2

6.6

NVP

80

79.5

99.4

5.9

80.1

100.2

7.6

 

640

662.8

103.5

9.0

658.3

102.9

7.0

 

5120

5044.0

98.5

6.1

4981.3

97.3

8.1

EFV

80

73.7

92.1

7.1

77.4

96.7

9.2

 

640

651.8

102.0

7.7

648.7

101.4

8.4

 

5120

5178.0

101.1

5.1

5190.0

101.4

6.9

LPV

80

91.1

113.8

6.6

85.4

106.7

10.9

 

800

885.0

110.8

3.6

844.7

105.7

7.5

 

8000

7900

98.7

3.8

7767.3

97.1

7.3

RTV

15

14.9

99.1

9.6

15.0

99.7

9.0

 

150

152.6

101.9

9.0

161.1

107.4

7.0

 

1500

1494.0

99.8

4.9

1592.7

106.3

6.1

Table 5: Precision and accuracy of AZT, 3TC, d4T, EFV, NVP, LPV and RTV in plasma (n=5).