|
Factor |
Level |
Mean % assay(n=3), % RSD of results |
Atorvastatin |
Ezetimibe |
Fenofibrate |
| Flow rate
(mL/min) |
0.8 |
100.6, 0.79 |
100.4, 0.49 |
100.2, 0.32 |
1.0 |
98.6, 0.40 |
98.6, 1.25 |
99.6, 0.83 |
| Column oven
temperature (°C) |
45 |
99.1, 0.82 |
99.0, 0.51 |
99.5, 1.33 |
35 |
99.8, 1.53 |
100.6, 1.21 |
99.9, 1.18 |
| Separation
Column |
Column Ia |
100.9, 0.69 |
99.6, 1.10 |
99.4, 0.58 |
Column IIb |
99.8, 1.53 |
101.2, 0.28 |
100.2, 1.16 |
| Measurement
wavelength (nm) |
239 |
99.35, 1.53 |
99.6, 1.50 |
99.9, 0.76 |
241 |
99.91, 1.07 |
98.4, 0.48 |
99.8, 0.59 |
|
