Retention time (min) Theoretical plates (N>2000)b Tailing factor (T £ 2)b Capacity factor (k’ > 2)b Assay (%)
Method proposeda 7.6 8367 1.4 5.3 100.8
Mobile phase: pH 7.0 7.2 8369 1.4 5.0 99.2
Mobile phase: pH 8.0 8.1 8088 1.4 5.8 99.1
flow rate: 1.0 mL·min-1 8.8 8937 1.4 8.6 100.7
Analytical Column Merck C8 (125×4.6 mm) *1.0 mL·min-1 3.7 2702 2.0 2.1 100.6
Table 3: Evaluation of robustness for the milnacipran capsules LC assay.