Time (days)

Measurement

Intravenous

Intramuscular

0

WBC
G/AG
N/M

14.30(2.41)(10.0-16.0)c
0.81(0.21)(0.55-1.10)c
0.14 (0.03)(0.11-0.17)c

13.30(2.59)(9.0-15.5)b
0.81(0.25)(0.50-1.10)c
0.14 (0.02)(0.12-0.17)c

1

WBC
G/AG
N/M

30.00(5.70)(23.0-37.0)a
3.18(0.46)(2.60-3.80)a
NS

27.60(4.93)(21.0-34.0)a
2.90(0.60)(2.10-3.70)a
NS

2

WBC
G/AG
N/M

19.8(3.83)(15.0-24.0)b
1.98(0.30)(1.60-2.40)b
NS

15.40(2.41)(12.0-18.0)b
1.48(0.30)(1.10-1.90)b
NS

3

WBC
G/AG
N/M

16.40(2.41)(13.0-19.0)bc
2.12(0.49)(1.50-2.70)b
0.23(0.05)(0.17-0.29)b

14.80(2.59)(11.0-18.0)b
0.86(0.31)(0.50-1.20)c
0.20(0.04)(0.15-0.26)bc

4

WBC
G/AG
N/M

16.00(2.74)(12.0-19.0)bc
0.86(0.04)(0.80-0.91)c
0.30 (0.07)(0.21-0.39)ab

13.80(2.86)(10.0-17.0)b
0.78(0.28)(0.45-1.10)c
0.25 (0.02)(0.19-0.32)ab

5

WBC
G/AG
N/M

14.60 (1.14)(13.0-16.0)c
0.80(0.16)(0.60-1.00)c
0.36 (0.05)(0.29-0.43)a

12.80 (2.39)(10.0-16.0)b
0.80(0.20)(0.55-1.00)c
0.29 (0.06)(0.21-0.37)a

LSD

WBC
G/AG
N/M

4.381
0.418
0.069

4.037
0.455
0.062

(a,b,c)Means with the same letter in the same column measurement are not significantly different at (Pr>F 0.0001). NS = Not sampled. LSD = Least significant difference.
Table 4: Mean (SD) and ranges of total blood cell counts (WBC,103mm3-1), blood granulocyte/agranulocyte ratios (G/AG) and BAL fluid neutrophil/macrophage ratios (N/M) in groups of 5 calves infected experimentally with Pasteurella multocida and treated with florfenicol either intravenously or intramuscularly.