| % Drug release (n=3) |
| TIME |
PD (Mean ± SD) |
PM (Mean ± SD) |
KN (Mean ± SD) |
| ( min) |
R |
S |
R |
S |
R |
S |
| 5 |
83.43 ± 2.16 |
81.15 ± 2.73 |
85.71 ± 2.29 |
84.50 ± 2.67 |
85.26 ± 2.91 |
83.27 ± 3.42 |
| 15 |
90.32 ± 2.41 |
92.49 ± 3.49 |
95.47 ± 3.52 |
96.88 ± 1.91 |
95.75 ± 2.75 |
93.10 ± 3.25 |
| 30 |
97.54 ± 3.36 |
98.38 ± 2.19 |
98.91 ± 3.61 |
99.09 ± 3.31 |
99.31 ± 2.64 |
98.91 ± 2.06 |
| 45 |
94.12 ± 2.29 |
94.13 ± 3.29 |
95.83 ± 2.49 |
96.39 ± 2.16 |
98.45 ± 2.39 |
94.20 ± 3.26 |
| 60 |
91.18 ± 1.89 |
89.88 ± 3.35 |
90.41 ± 2.05 |
91.09 ± 3.25 |
93.98 ± 3.34 |
91.31 ± 3.27 |
| TIME |
SE1 (Mean ± SD) |
SE2 (Mean ± SD) |
SE3 (Mean ± SD) |
| ( min) |
R |
S |
R |
S |
R |
S |
| 5 |
84.13 ± 3.41 |
82.15 ± 3.12 |
86.17 ± 2.91 |
85.45 ± 3.36 |
85.78 ± 2.90 |
87.64 ± 2.28 |
| 15 |
94.56 ± 2.42 |
92.29 ± 3.31 |
96.89 ± 2.75 |
95.28 ± 2.36 |
96.36 ± 2.64 |
94.24 ± 3.27 |
| 30 |
98.97 ± 2.28 |
98.85 ± 2.79 |
100.12 ± 2.36 |
98.91 ± 2.78 |
100.07 ± 2.97 |
96.19 ± 3.28 |
| 45 |
96.80 ± 2.48 |
95.37 ± 3.17 |
99.57 ± 2.68 |
94.46 ± 2.42 |
96.82 ± 3.17 |
99.64 ± 2.58 |
| 60 |
92.47 ± 2.26 |
90.24 ± 3.23 |
95.71 ± 3.63 |
90.68 ± 3.39 |
92.85 ± 2.74 |
90.02 ± 3.13 |
|
