Validation parameters PAR DPH PAP
PLS PCR PLS PCR PLS PCR
Mean ± SD 101.00± 1.20 100.61± 1.42 100.09± 0.75 100.40± 1.10 99.41± 1.16 99.51± 1.35
RMSEP 0.1025 0.1184 0.0106 0.1166 0.0836 0.00707
Predicted versus actual concentration plot  
a-Slope
b-Intercept
c-Correlation coefficient (r)
1.0050
0.0100
0.9996
1.0106
-0.0139
0.9998
1.0011
-0.0187
0.9996
1.0029
0.0042
0.9994
0.9837
0.0637
0.9996
1.0189
-0.1065
0.9994
Table 3: Results of assay validation parameters of the proposed multivariate method for determination of Paracetamol, Diphenhydramine Hydrochloride and P-aminophenol.