Moxifloxacin Analytical Method Validation-Assay

Method Parameter

Method Precision

Std. wt. &
Dilution

44.02

5

Tablet Wt.

Spl. wt. &
Dilution

Wt. of sample
 taken

5

Label claim
(mg)

400

100

20

675.01

200

200

Potency (%)

98.8

Molecular factor for Moxifloxacin

0.917

 

 

 

 

Std. No.

Standards

USP
 Tailing

Weight of
sample taken

Area of
sample

Assay %

Average
      (%)

STDEV

% RSD

1

2310915

1.54

1353.34

2337254

101.04

100.4

0.61837

0.62

2

2290693

1.54

1351.89

2321427

100.46

3

2300684

1.54

1358.15

2317128

99.81

4

2300777

1.54

1353.97

2341249

101.16

5

2300755

1.54

1355.02

2324067

100.34

 

 

 

1356.39

2310208

99.64

Average

2300765

1.54

1354.79

2325222

100.41

STDEV

7149.73

0.00

Limits

% RSD of 6 replicate injections is not more than 2

%RSD

0.31

0.0

Table 10: