| Moxifloxacin Analytical Method Validation-Assay |
| Method Parameter |
Intermediate Precision |
Std. wt. &
Dilution |
44.13 |
5 |
Tablet Wt. |
Sample wt. &
Dilution |
Wt. of sample
taken |
5 |
Label claim
(mg) |
400 |
| 100 |
20 |
675.01 |
200 |
200 |
Potency (%) |
98.8 |
| Molecular factor for Moxifloxacin |
0.917 |
|
|
|
|
| Std. No. |
Standards |
USP
Tailing |
Wt. of
sample taken |
Area of
sample |
Assay % |
Average
(%) |
STDEV |
% RSD |
| 1 |
2315498 |
1.52 |
1351.91 |
2303175 |
99.22 |
99.4 |
0.388 |
0.39 |
| 2 |
2302693 |
1.52 |
1360.40 |
2318575 |
99.26 |
| 3 |
2314434 |
1.52 |
1355.75 |
2314650 |
99.43 |
| 4 |
2321577 |
1.52 |
1353.39 |
2305262 |
99.20 |
| 5 |
2330688 |
1.52 |
1352.51 |
2325271 |
100.13 |
| 6 |
|
|
1356.55 |
2306776 |
99.03 |
| Average |
2316978 |
2 |
1355 |
2312285 |
99.38 |
| STDEV |
10269.35 |
0.00 |
Limits |
% RSD of 6 replicate injections is not more than 2 |
| %RSD |
0.4 |
0.0 |
|
