Moxifloxacin Analytical Method Validation-Assay

Method Parameter

Method & Intermediate Precision combined

Method Precision

 

Intermediate Precision

 

 

 

 

S.No.

% Drug
 content

S.No.

% Drug
 content

Difference

Average of both
Method &
Intermediate
 precision

STDEV of both
Method &
Intermediate
 precision

%RSD of both
Method &
Intermediate
 precision

1

101.04

1

99.2

1.8

99.9

0.730

0.73

2

100.46

2

99.3

1.2

3

99.81

3

99.4

0.4

4

101.16

4

99.2

2.0

5

100.34

5

100.1

0.2

6

99.64

6

99.0

0.6

Limits: Overall RSD when compared with Method precision should be not more than 2%.

Table 12: