Concentration of MEH: DF: MET DDRD HDDR % Recoveryb MEH DF MET MEH DF MET 3: 15: 22.5a 97.00 99.98 102.58 99.16 102.73 102.56 15: 15: 15 96.47 105.50 102.00 100.14 98.47 101.86 10: 15: 20 98.70 106.66 102.10 99.97 100.29 102.04 4: 8: 9 103.00 104.41 99.78 99.37 97.80 99.66 4: 12: 8 103.00 102.08 102.75 97.15 101.34 102.67 Mean ± RSD%. 99.63 ± 3.193 103.73 ± 2.594 101.84 ± 1.173 99.16 ± 1.203 100.13 ± 2.024 101.76 ± 1.199 aThe same ratio of Dimetrol® tablets. bAverage of three determinations.

Table 3: Results of determination of Mebeverine HCl, Diloxanide Furoate and Metronidazole in synthetic mixtures using the proposed spectrophotometric methods.