Treatments

mg/kg

x2 test vs.
Quick Fat

Scores

Fast (2–5 h)

Medium (5–8 h)

Slow (over 8 h)

CE-7

  

  p = 0.148

3

4

1

Quick Fat

    

0

7

1

WEA (Quick Fat)

  1000

  p = 0.022*

5

3

0

EEA (Quick Fat)

  1000

  p = 0.008**

6

2

0

WEA: water extract of agarwood

 

EEA: ethanol extract of agarwood

 

    
Mice received a regimen of CE-7 or Quick Fat for a week. A vehicle (10% gum arabic), WEA, and EEA at 1,000 mg/kg were orally administered to the mice. Carmine (10 mg/body) was orally administered to the mice just before administration of the samples, and then the weights of carmine-containing feces were measured during consecutive 1-h periods over 8 h. Carmine egestion was determined as egestion of carmine-containing fecal beads over 30 mg. The carmine egestion point was classified into three groups; Fast: egested in 2–5 h, Medium: egested in 5–8 h, Slow: not egested in 8 h after administration n = 8.
Table 1: Effects of WEA and EEA on carmine egestion in mice.