Stabilisers, surfactants and co- surfactants Solubility(mg/g)
Stabilizers
Plasdone K 90 D: 1 % 0.387 ± 0.0176
Plasdone K 90 D: 5 % 0.383 ± 0.0381
Plasdone K 90 D 10 % 0.415 ± 0.049
Poloxamer 407:1% 0.2665 ± 0.047
Poloxamer 407: 5% 0.731 ± 0.0721
Poloxamer 407:10 % 8.785 ± 0. 31
Poloxamer 188:1 % 0.156 ± 0.0622
Poloxamer 188: 5 % 0.1745 ± 0.02
Poloxamer 188 :10 % 0.35 ± 0.070
Surfactants and co -surfactants
Transcutol P 62.38 ± 1.84
Glycerine 0.094 ± 0.0014
Propylene glycol 3.5 ± 0.355
Softigen 767 16.3 ± 0.5
Gelucire 44/14 13.245 ± 0.53
Tween 60   3.4 ± 0.42
Tween 80 72.94 ± 1.46
Tween 20 92.11 ± 6.25
Solutol HS 15 2.5 ± 0.35
Cremophor EL 3.01 ± 0.34
Cremophor RH 40 6.2 ± 0.56
Labrasol 0.01515 ± 0.300
Table 5: Solubility of curcumin in different stabilizers, surfactants and cosurfactants.