Curcumin

Celecoxib

Sr. No

Exposure condition

Time
(h)

Drug remaining
(μg/mL)

% of drug remaining

% RSD

Stability of celecoxib under subjected conditions

1

Photo  degradation

0.5

15.33

76.65

0.82

Stable

2

Oxidation

1.0

6.60

33.00

1.25

Stable

3

Base degradation

0.6

7.60

38.01

0.69

Stable

4

Acid  degradation

1.0

8.058

40.29

0.089

Stable

5

Heat degradation

1.0

20.04

100.203

1.69

Stable

Table 2: Forced degradation studies of curcumin (95 %) and celecoxib.