Sample Ezetimibe Area counts
(µv*sec)
Atorvastatin Area counts
(µv*sec)
Ezetimibe Atorvastatin
Assay
25mg
Percent
Degradation
Assay
25mg
Percent Degradation
Sample (1 N HCl, 5ml) 197865 242001 22.63 9.48 22.12 11.52
Sample(1 N NaOH, 5ml) 195122 262735 23.75 5 22.09 11.64
Sample (H2O2 30%, 5ml) 196802 260685 21.88 12.48 2407 3.72
Sample Thermal Deg.(105°C/1hr) 185449 253395 20.63 17.48 23.79 4.84
Sample photolytic Deg.
(2600 Lux/24 hr)
187514 452202 24.19 13.34 23.76 4.96
Table 5: Degradation Study for Ezetimibe and Atorvastatin.