|
Days |
Control |
Standard
(Ciphadin) |
Ethanol
extract |
| Wound area |
% of
wound contraction |
Wound area |
% of
wound contraction |
Wound area |
% of
wound contraction |
| 0day |
535 ± 18.3
(0.0%) |
- |
508 ± 38.5
(0.0%) |
- |
520 ± 34.3
(0.0%) |
- |
| 3day |
508 ± 21.0
(5.04%) |
94.9 |
450 ± 34.4
(11.42%) |
88.5 |
406 ± 29.1
(21.93%) |
78.0 |
| 5day |
460 ± 17.6
(14.01%) |
85.9 |
320 ± 28.8a
(37.00%) |
62.9 |
326 ± 32.8a
(37.31%) |
62.6 |
| 7day |
400 ± 12.0
(25.23%) |
74.7 |
264 ± 31.5a
(48.03%) |
51.9 |
194 ± 31.0b
(62.69%) |
37.3 |
| 9day |
369 ± 16.5
(31.02%) |
68.9 |
186 ± 25.2a
(63.38%) |
36.6 |
82 ± 35.4b
(84.23%) |
15.7 |
| 11day |
309 ± 14.5
(42.24%) |
57.7 |
104 ± 22.0b
(79.52%) |
20.4 |
48 ± 28.2b
(90.77%) |
9.2 |
| 13day |
278 ± 13.3
(48.03%) |
51.9 |
80 ± 18.4b
(84.25%) |
15.7 |
16 ± 10.4b
(96.92%) |
3.0 |
| 15day |
208 ± 12.7
(61.12%) |
38.8 |
46 ± 21.8b
(90.94%) |
9.0 |
6 ± 8.1b
(98.85%) |
1.1 |
| 17day |
172 ± 10.2
(67.85%) |
32.1 |
8 ± 7.1b
(98.42%) |
1.5 |
0.0b
(100%) |
0 |
| 19day |
166.12.0
(68.97%) |
31.0 |
0.0b
(100%) |
0 |
0.0b
(100%) |
0 |
| Epithelization time (days) |
23 |
17 |
15 |
Values are mean ± SEM (n=6)
P values vs. respective control by Dunnet’s t-test: ap<0.01, bp<0.001. |
