Groups        Doses            Granuloma (mg) Granuloma breaking strength (g) Hydroxyproline content (µg/ml)
    Wet wt     Dry wt
Control - 68.1 ± 8.9 24.9 ± 3.4 256.8 ± 2.15 1.868 ± 0.03
Standard (Ciphadin) 50 mg/animal 146.4 ± 4.43* 54.9 ± 3.19* 347.8 ± 3.8* 5.267 ± 0.02*
Desmodium gyrans ethanol extract 100 mg/kg bw 73 ± 4.16* 27.67 ± 2.33* 283.3 ± 2.7* 3.825 ± 0.04*
Desmodium gyrans ethanol extract 200 mg/kg bw 91.33 ± 2.33* 34.33 ± 0.88* 335.0 ± 4.46* 4.847 ± 0.04*
Desmodium gyrans ethanol extract 400 mg/kg bw 92.67 ± 2.33* 37 ± 2.65* 383.2 ± 3.34* 5.143 ± 0.03*
Values are mean ± SEM (n=6)
P values vs. respective control by Dunnet’s t-test: *p<0.05
Table 2: Effect of the ethanol extract and starndard ointment on various parameters of dead space wound model in rats.