Ratio(ng mL
-1
)
Recovery
a
% ± RSD
Amantadine
Memantine
Amantadine
Memantine
1
1
99.79 ± 1.07
99.04 ± 1.89
1
4
100.05 ± 2.00
100.46 ± 1.04
2
1
98.86 ± 1.66
100.18 ± 1.07
a
Mean of five different experiments.
Table 3:
Specificity of the proposed TOF ES-MS method for simultaneous analysis of amantadine and memantine in drug substances.
