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Figure 8: Typical HPLC chromatograms obtained from Losartan under acidic
stress conditions: 1- Methanolic solution under 1.0 M HCl at 25°C after 3 days. 2- Methanolic solution under 1.0 M HCl at 70°C after 3 days. 3- Methanolic solution under 1.0 M HCl at 25°C after 7 days. 4- Methanolic solution under 1.0 M HCl at 70°C after 7 days. 5- Methanolic solution under 1.0 M HCl at 25°C after 14 days. 6- Methanolic solution under 1.0 M HCl at 70°C after 14 days. |