Figure 9: Typical HPLC chromatograms obtained from Valsartan under acidic stress conditions:
1- Methanolic solution under 1.0 M HCl at 25°C after 3 days.
2- Methanolic solution under 1.0 M HCl at 70°C after 3 days.
3- Methanolic solution under 1.0 M HCl at 25°C after 7 days.
4- Methanolic solution under 1.0 M HCl at 70°C after 7 days.
5- Methanolic solution under 1.0 M HCl at 25°C after 14 days.
6- Methanolic solution under 1.0 M HCl at 70°C after 14 days.