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Figure 10: Typical HPLC chromatograms obtained from Irbesartan under
stress alkaline conditions: 1-Methanolic solution under 1.0 M NaOH at 25°C after 3 days. 2-Methanolic solution under 1.0 M NaOH at 70°C after 3 days. 3-Methanolic solution under 1.0 M NaOH at 25°C after 7 days. 4-Methanolic solution under 1.0 M NaOH at 70°C after 7 days. 5-Methanolic solution under 1.0 M NaOH at 25°C after 14 days. 6-Methanolic solution under 1.0 M NaOH at 70°C after 14 days. |