Figure 10: Typical HPLC chromatograms obtained from Irbesartan under stress alkaline conditions:
1-Methanolic solution under 1.0 M NaOH at 25°C after 3 days.
2-Methanolic solution under 1.0 M NaOH at 70°C after 3 days.
3-Methanolic solution under 1.0 M NaOH at 25°C after 7 days.
4-Methanolic solution under 1.0 M NaOH at 70°C after 7 days.
5-Methanolic solution under 1.0 M NaOH at 25°C after 14 days.
6-Methanolic solution under 1.0 M NaOH at 70°C after 14 days.