Drug name Recovery ± SD Calculated t-values Calculated F-values
Proposed methods Reference method
Irbesartan (%) 99.26 ± 0.76 98.98 ± 1.10 1.36(2.57) 0.48(5.05)
Losartan (%) 100.33 ± 0.63 100.06 ± 0.43 1.53(2.57) 2.21(5.05)
Telmisartan (%) 100.65 ± 1.64 99.68 ± 1.41 1.68(2.57) 1.36(5.05)
Valsartan (%) 98.98 ± 0.42 99.79 ± 0.62 2.05(2.57) 0.46(5.05)
(Where the Tabulated t-values and F-ratios at p=0.05 are 2.57 and 5.05)
Table 8: Statistical comparison of the proposed and published methods for determination of Irbesartan, Losartan potassium, Telmisartan and Valsartan respectively in their dosage forms by reported method (T-student test) and (F-test for variance).