Recovery (%)
a
CARV
HCT
Method
3
D
4
D
1
DD
3
D
4
D
1
DD
Wavelength (nm)
245.9
247.4
236.1
230.2
226.9
261.1
Added (µg.mL
-1
)
CARV
HCT
8.0
2.0
100.00
99.50
100.01
99.32
99.75
101.05
8.0
4.0
101.87
99.73
101.05
101.17
100.15
100.08
8.0
6.0
100.90
100.75
102.00
100.87
101.07
101.12
8.0
8.0
100.00
100.01
101.02
101.60
100.40
100.09
12.0
10.0
99.47
99.90
99.89
100.33
99.37
102.00
14.0
10.0
99.68
100.02
99.97
99.92
99.58
100.06
16.0
10.0
100.44
99.80
100.30
99.70
100.03
99.63
18.0
10.0
99.76
99.54
99.61
100.04
100.11
99.89
Mean recovery (%)
100.26
99.91
100.48
100.37
100.06
100.49
RSD%
0.79
0.39
0.81
0.78
0.53
0.81
a
Mean of three independent analyses
Table 2:
Determination of carvedilol (CARV) and hydrochlorothiazide (HCT) in laboratory prepared mixtures using
3
D,
4
D, and
1
DD methods.