Method     Amount, µg.mL-1               Carvedilol (CARV)             Hydrochlorothiazide (HCT)
  Taken   Added Found ± RSDa Recovery ± RSD (%) Found ± RSDa Recovery ± RSD (%)
3D   245.9 nm 230.2 nm
10.0 5.0 4.94 ± 0.05 98.80 ± 1.01 4.99 ± 0.04 99.80 ± 0.80
10.0 7.5 7.60 ± 0.6 101.33 ± 0.79 7.48 ± 0.03 99.73 ± 0.40
10.0 10.0 9.97 ± 0.09 99.70 ± 0.90 10.05 ± 0.06 100.50 ± 0.60
Mean ± RSD(%)   99.94 ± 0.90   100.01 ± 0.60
4D   247.4 nm 226.9 nm
10.0 5.0 5.02 ± 0.04 100.40 ± 0.80 4.97 ± 0.05 99.40 ± 1.101
10.0 7.5 7.47 ± 0.05 99.60 ± 0.67 7.55 ± 0.04 100.66 ± 0.53
10.0 10.0 10.03 ± 0.09 100.30 ± 0.90 9.95 ± 0.07 99.50 ± 0.70
Mean ± RSD(%)   100.10 ± 0.79   99.85 ± 0.75
1DD   236.1 nm 261.1 nm
10.0 5.0 4.98 ± 0.03 99.60 ± 0.60 5.02 ± 0.02 100.40 ± 0.40
10.0 7.5 7.51 ± 0.04 100.13 ± 0.53 7.49 ± 0.05 99.87 ± 0.67
10.0 10.0 9.99 ± 0.07 99.90 ± 0.70 10.02 ± 0.08 100.20 ± 0.80
Mean ± RSD(%)   99.88 ± 0.61   100.16 ± 0.62
a Mean of five independent analyses
Table 3: Recovery data by standard addition method for CARV and HCT in drug formulation (Co-dilatrol tablets).