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Figure 6: Effect of P2X7 agonists and P2X7 antagonists on VEGF production in RBL-2H3. RBL-2H3 cells were pre-incubated with vehicle, oxATP (300 μM) or A438079 (100 μM), and incubated with vehicle, ATP (1-3 mM), BzATP (100 μM) for 24 h. The concentration of VEGF in culture medium was measured by ELISA. The data represent the means ± SE. Statistically significant differences are indicated by **(p<0.01). |