Time
(min)
Atorvastatin Celecoxib Atorvastatin Celecoxib Atorvastatin Celecoxib
pH 4 pH 6.8 pH 9
0 115.67 101.47 123.96 127.59 108.63 101.74
30 98.42 98.00 99.07 98.85 99.78 99.04
60 98.87 99.79 98.96 99.23 98.94 98.76
90 98.38 100.64 99.58 98.80 99.36 98.42
120 98.76 100.46 99.32 98.19 99.57 98.67
150 98.52 100.38 99.10 98.84 98.36 98.12
180 98.31 99.45 98.69 98.42 99.17 98.63
Table 7: Interaction studies by RP-HPLC.