|
Papp-PAMPA (10-6) (cm/s) |
Papp-Caco-2(10-6) (cm/s) |
Compound |
6/7.4 |
7.4/7.4 |
6/7.4 |
7.4/7.4 |
Genistein |
2.94 ± 0.49 |
1.50 ± 0.18 |
52.86 ± 3.77 |
37.75 ± 1.15 |
DHG |
0.74 ± 0.18 |
0.39 ± 0.03 |
99.44 ± 0.48 |
55.47 ± 2.70 |
Daidzein |
0.35 ± 0.04 |
0.45 ± 0.04 |
67.97 ± 2.76 |
40.64 ± 0.91 |
DHD |
0.48 ± 0.06 |
0.21 ± 0.10 |
99.72 ± 3.76 |
52.78 ± 0.64 |
Data are presented as the mean ± S.D. |
DHG, dihydrogenistein; DHD, dihydrodaidzein; PAMPA, artificial membrane
permeation assay |