S.No
Chemical and Physical Treatments to Promote
1
Aggregation
2
Fragmentation
3
Precipitation
4
Dephosphorylation
5
Deamidation
6
Deglycosylation
7
Hydrolysis
8
Oxidation
9
Disulfide bond exchange
10
Ligand release
Table 5:
Purposeful (forced) degradation of biotechnology products.