Figure 4: A model of the solid/liquid interface with specific adsorption on the imprinted layer and non-specific adsorption of the substrate, showing the specific structure of adsorbed drug depends on the balance between adsorption and adsorption energy of the imprint The structure of intact water layer near polymer surface is formed (dash line) which is influenced by the polar anchoring of the monolayer to the interface between polymer surface and adsorbed species in case of specific adsorption on the polymer surface and non-specific adsorption, respectively [112].