Coatings/Modifications Advantages References
Polyethylene glycol (PEG) Neutral, escape RES, long circulation, prevents degradation  [90-92]
Dextran Biocompatible and polar interactions  [93-95]
Chitosan Easier functionalization, easily available, biocompatible, cationic hydrophilic polymer  [96-97]
Polyethyleneimine (PEI) Facilitates endosomal release by forming complex with DNA  [98-100]
Liposomal & Micellar coatings Good encapsulation, sequestration and protection of drugs inside body [101]
Co-polymers Different functionalities of constituents [ 102-103]
Table 2: Strategies for surface modification for nanoparticles.