Figure 1: Chemical Structures of a- Amlodipine besylate b- Atorvastatin calcium c- Losartan potassium d- Valsartan Amlodipine besylate is 3-Ethyl5-methyl (4RS)-2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzene sulphonate. Atorvastatin calcium is R-(βR,δR)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino) carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate Losartan Potassium is 1H-Imidazole-5-methanol,2-butyl-4-chloro-1-[[2’-(lH-tetrazol-5-yl) [1,1’-biphenyl]-4-yl] methyl] monopotassium salt. Valsartan is N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl) [1,1′-biphenyl]-4-yl] methyl]-L-valine.