| Item |
Amlodipine besylate |
Losartan potassium |
Valsartan |
Atorvastatin calcium |
| Linear range (µg/ml) |
2-12 |
10-60 |
16-96 |
4-24 |
| Detection limit (µg/ml) |
0.03 |
0.18 |
0.15 |
0.007 |
| Quantitation limit (µg/ml) |
0.1 |
0.54 |
0.45 |
0.024 |
| Regression data |
|
|
|
|
| N |
5 |
5 |
5 |
5 |
| Slope (b) |
64.62 |
75.39 |
64.49 |
70.96 |
| Standard deviation of the slope |
0.71 |
0.1 |
0.065 |
0.69 |
| Intercept (a) |
6.0 |
8.39 |
30.19 |
33.99 |
| Standard deviation of the intercept |
0.62 |
4.09 |
2.95 |
0.17 |
| Correlation coefficient ® |
0.9998 |
0.9997 |
0.9998 |
0.9998 |
| Standard error of regression |
0.07 |
0.40 |
0.47 |
0.17 |
|
| (Y=a+bC, where C is the concentration of the compound (µg/ml) and Y is the drug peak area) |
| Table 4: Calibration data was resulted from method validation of Amlodipine besylate, Losartan potassium, Valsartan and Atorvastatin calcium respectively. |