Figure 3: Typical HPLC chromatograms obtained from 20 μl injections of Amlodipine Besylate Amlodipine impurity A, Atorvastatin impurity A, Atorvastatin Calcium, Atorvastatin impurity C and Amlodipine impurity B respectively under optimized chromatographic conditions. (Ascending order)
1. 2- At 238 and 242 nm
3. 4- at 1.1 and 1.3 ml/min
5. 6-at phosphate buffer pH=5.2 and 5.8
7. 8-at 33% and 37% of acetonitrile