Drug Cmax [µg/ml] Tmax [hr] T1/2 [hr] AUC
[µg/ml*hr]
PG 15.27 ±0.03 3 3.6 130.59 ±2.10
PG plus sucralose 13.03 ± 0.1 3 3.6 118.52 ±2.90
P value 0.008 P values < 0.05 0.001
Table 8: Serum concentration–time profile kinetic parameters.