MIX NO Mix Ratio MOX: HCT Taken (µg/ml) Found* recovery %
Absorbance Subtraction Amplitude Modulation Extended Ratio Subtraction
MOX HCT MOX HCT MOX HCT MOX HCT
1 1:1 7 7 100.43 100.57 99.71 100.43 99.43 100.57
2 1:1.67** 3 5 99.00 99.60 99.00 99.60 101.67 99.40
3 1.67:1 5 3 99.20 99.00 100.80 101.33 99.20 101.00
4 1:2 4 8 99.25 100.5 100.75 100.50 101.00 100.75
5 2:1 8 4 100.50 98.75 100.63 100.75 99.63 99.25
6 1:3 2 6 102.00 101.00 101.50 100.67 101.50 99.33
7 3:1 6 2 99.50 98.50 99.50 99.00 99.67 98.50
8 1:1.44 9 13 99.44 99.54 100.44 100.54 100.67 99.69
Mean 99.92 99.68 100.29 100.35 100.35 99.81
S.D 1.010 0.922 0.819 0.724 0.981 0.872
R.S.D % 1.011 0.925 0.817 0.721 0.978 0.874
*Average of three determinations.
** Corresponding to their ratio in pharmaceutical formulation
Table 5: Determination of the studied drugs in the laboratory prepared mixtures by the proposed methods