| MIX NO |
Mix Ratio MOX: HCT |
Taken (µg/ml) |
Found* recovery % |
| Absorbance Subtraction |
Amplitude Modulation |
Extended Ratio Subtraction |
| MOX |
HCT |
MOX |
HCT |
MOX |
HCT |
MOX |
HCT |
| 1 |
1:1 |
7 |
7 |
100.43 |
100.57 |
99.71 |
100.43 |
99.43 |
100.57 |
| 2 |
1:1.67** |
3 |
5 |
99.00 |
99.60 |
99.00 |
99.60 |
101.67 |
99.40 |
| 3 |
1.67:1 |
5 |
3 |
99.20 |
99.00 |
100.80 |
101.33 |
99.20 |
101.00 |
| 4 |
1:2 |
4 |
8 |
99.25 |
100.5 |
100.75 |
100.50 |
101.00 |
100.75 |
| 5 |
2:1 |
8 |
4 |
100.50 |
98.75 |
100.63 |
100.75 |
99.63 |
99.25 |
| 6 |
1:3 |
2 |
6 |
102.00 |
101.00 |
101.50 |
100.67 |
101.50 |
99.33 |
| 7 |
3:1 |
6 |
2 |
99.50 |
98.50 |
99.50 |
99.00 |
99.67 |
98.50 |
| 8 |
1:1.44 |
9 |
13 |
99.44 |
99.54 |
100.44 |
100.54 |
100.67 |
99.69 |
| Mean |
99.92 |
99.68 |
100.29 |
100.35 |
100.35 |
99.81 |
| S.D |
1.010 |
0.922 |
0.819 |
0.724 |
0.981 |
0.872 |
| R.S.D % |
1.011 |
0.925 |
0.817 |
0.721 |
0.978 |
0.874 |
|
*Average of three determinations.
** Corresponding to their ratio in pharmaceutical formulation |
| Table 5: Determination of the studied drugs in the laboratory prepared mixtures by the proposed methods |