Pharmaceutical
preparation

Absorbance
Subtraction

Amplitude
Modulation

Extended Ratio
Subtraction

Chemometry

MOX

HCT

MOX

HCT

MOX

HCT

MOX

HCT

PLS

PCR

PLS

PCR

Fempress®
tabletsᵃ
( Contain 25
MG MOX+15
mg HCT)
B.N 100251

99.41
± 1.073

100.47
± 0.880

99.76
± 0.922

100.27
± 0.809

99.20
± 0.984

99.99
± 0.936

100.15
± 1.101

100.2
± 1.168

100.47
± 1.086

100.41
± 1.027

Standard
additionᵇ
technique
Mean ± S.D

100.92
±
1.283

99.92
±
1.233

100.54
±
1.162

99.33
±
1.041

99.39
±
1.136

100.75
±
1.090

101.04
±
1.249

101.08
±
1.377

101.83
±
1.258

101.75
±
1.090

a Average of five determinations.
b Average of three determinations.
Table 6: Determination of MOX and HCT in their pharmaceutical formulation and application of standard addition technique