Variations Chlordiazepoxide Mebeverine
Retention time Peak area Plate count % RSD Retention time Peak area Plate count % RSD
PH=6.5 7.165 1757140 17902 0.32 3.298 561797 8790 0.1
PH=7.5 9.24 2185148 16317 0.11 4.23 697128 9395 0.11
Flow rate 1.1mL/min 6.44 1446089 11260 0.21 2.84 465104 6662 0.26
Flow rate 0.9ml/min 9.24 218514 16317 0.23 4.23 697128 9395 0.2
Table 8: Results of Robustness study by RP-HPLC